Bacterial Co- or Superinfection in Patients Treated in Intensive Care Unit with COVID-19- and Influenza-Associated Pneumonia

Viral pneumonia is frequently complicated by bacterial co- or superinfection (c/s) with adverse effects on patients’ outcomes. However, the incidence of c/s and its impact outcomes patients might be dependent type viral pneumonia. We performed a retrospective observational study in confirmed COVID-19 (CP) influenza (IP) from 01/2009 to 04/2022, investigating using competing risk model mortality these tertiary referral center multivariate logistic regressions. Co-infection was defined as pulmonary pathogenic bacteria tracheal aspirate bronchoalveolar lavage within 48 h after hospitalization. Superinfection detected examined 114 CP 76 IP. Pulmonary co-infection 15 (13.2%), 50 (43.9%) patients. A total 5 (6.6%) co-infections (p = 0.2269) 28 (36.8%) superinfections 0.3687) were IP The overall did not differ between patients, an independent predictor for cohort high disease severity. found significantly higher probability compared 0.0017).